Budget Impact Analysis Of Tofacitinib For Rheumatoid Arthritis From The Perspective Of The Brazilian Private Healthcare System.
نویسندگان
چکیده
Tofacitinib is an active immunosuppressant: oral administration (unnecessary cold chain) acts as a potent and selective inhibitor of Janus kinase family (JAK), more specifically JAK3 and JAK1, with an important role in cytokine signal transduction that regulates survival, proliferation, differentiation and apoptosis of lymphocytes4. adequate response in monotherapy. may provide multiple benefits for patients, doctors . short half-life. innovative mechanism of action is considered beneficial to patients non-responsive to current therapy DMARD.4
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عنوان ژورنال:
- Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
دوره 18 7 شماره
صفحات -
تاریخ انتشار 2015